Download E-books Translational Research and Discovery in Gastroenterology: Organogenesis to Disease PDF

By Deborah L. Gumucio, Linda C. Samuelson, Jason R. Spence

Translational Gastroenterology: Organogenesis to Disease bridges the space among simple and medical study by means of offering details on GI (gastrointestinal) organ improvement came across via clinical inquiry, along scientific observations of obtained and congenital abnormalities. Paired chapters, written from easy technology and medical viewpoints, overview the main organic pathways and molecules at paintings in organ ontogeny and ailment. as well as a entire survey of GI organ improvement and pathologies, the publication additionally highlights version organisms and new components of analysis, with chapters dedicated to contemporary advances within the box of GI stem phone biology, and the opportunity of tissue engineering of GI organs.

The themes coated supply a special window onto present task within the box of gastroenterology, fostering stronger wisdom for developmental biologists in addition to for scientific practitioners.

Notable positive aspects comprise the following:

• uncomplicated technology chapters evaluate the molecular and mobile pathways of GI organ improvement along medical chapters studying organ-based ailments, final the distance among the bench and the clinic.

• spinoff organs – esophagus, abdominal, pylorus, small gut, colon, liver, and pancreas –as good as tissues corresponding to serosa and enteric fearful approach which are universal to a number of GI organs.

• Chapters detailing using version organisms – Drosophila, sea urchin, zebrafish, C. elegans, Xenopus – for uncomplicated discovery reviews are included.

• Chapters on GI stem cells and the potential of tissue engineering of the GI organs supply a view to the way forward for learn and remedy in those organs.

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